hyaluronic acid

noun

hy·​al·​uron·​ic acid ˌhī(-ə)l-yu̇-ˈrä-nik 

: a viscous glycosaminoglycan chiefly of the matrix of tissues that occurs especially in the vitreous humor, umbilical cord, synovial fluid, and loose connective tissue and serves especially as a structural element and lubricant

Examples of hyaluronic acid in a Sentence

Recent Examples on the Web

With three types of hyaluronic acid, ectoin, and the brand’s signature thermal spring water, the moisturizer restores hydration, repairs a weak skin barrier, and plumps sagging skin. —Essence Wiley, InStyle, 7 June 2026

Designed to brighten and tighten the delicate under-eye skin, the cooling formula is packed with caffeine, hyaluronic acid, niacinamide, and more hydrating ingredients. —Sophie Dodd, Travel + Leisure, 3 June 2026

It’s also formulated with hyaluronic acid to retain moisture and niacinamide to soothe and improve any irritation. —Caley Sturgill, Southern Living, 2 June 2026

The new brand has launched body care with face-grade ingredients, and this hydration heavy-hitter (it's got four weights of hyaluronic acid and plus ceramides) is as lightweight as serums get. —Jackie Fields, PEOPLE, 1 June 2026

Word History

Etymology

International Scientific Vocabulary

First Known Use

1934, in the meaning defined above

Rhymes for hyaluronic acid

• antacid
• placid

Medical Definition

hyaluronic acid

noun

hy·​al·​uron·​ic acid ˌhīl-yu̇-ˌrän-ik-  ˌhī-əl-yu̇- 

: a viscous glycosaminoglycan that occurs especially in the vitreous body, the umbilical cord, and synovial fluid and as a cementing substance in the subcutaneous tissue