hyaluronic acid

noun

hy·​al·​uron·​ic acid ˌhī(-ə)l-yu̇-ˈrä-nik 

: a viscous glycosaminoglycan chiefly of the matrix of tissues that occurs especially in the vitreous humor, umbilical cord, synovial fluid, and loose connective tissue and serves especially as a structural element and lubricant

Examples of hyaluronic acid in a Sentence

Recent Examples on the Web

Try out the difference for yourself with this bifurcated serum-and-cream offering that calms, hydrates, and firms thanks to said truffles, sure, but also hyaluronic acid, panthenol, ceramides, and other good-for-skin ingredients. — Stacia Datskovska, Footwear News, 5 Oct. 2026

The addition of aloe vera juice and hyaluronic acid helps soothe and hydrate skin that may feel a little irritated. — Glamour, 2 Oct. 2026

The moisturizing ingredients include a blend of glycerin, niacinamide, the aforementioned hyaluronic acid, and dimethicone, which serves as a silicone emollient. — Conçetta Ciarlo, Vogue, 2 Oct. 2026

As great as retinol is, dryness can come with the territory, so glycerin and hyaluronic acid step in to replenish moisture and keep skin feeling comfortable. — Christa Joanna Lee, Allure, 2 Oct. 2026

Word History

Etymology

International Scientific Vocabulary

First Known Use

1934, in the meaning defined above

Rhymes for hyaluronic acid

• antacid
• placid

Medical Definition

hyaluronic acid

noun

hy·​al·​uron·​ic acid ˌhīl-yu̇-ˌrän-ik-  ˌhī-əl-yu̇- 

: a viscous glycosaminoglycan that occurs especially in the vitreous body, the umbilical cord, and synovial fluid and as a cementing substance in the subcutaneous tissue